Fig. 2.13 Importance of proper protein structure for function. Correct structure of the protein enzyme is necessary to help molecules (i.e., substrates) react. Cofactors and coenzymes (e.g., minerals, vitamins) bind, helping enzymes work effectively. (See also: http://www.phschool.com/science/biology_place/labbench/lab2/ph.html) (Sources of images below. Used with permission.)

For animation, see: https://biology4isc.weebly.com/uploads/9/0/8/0/9080078/function_structure_of_enzymes_-_dnatube.com_-_scientific_video_and_animation_site_988.mp4



 

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Description Name: Microbiology ID: e42bd376-624b-4c0f-972f-e0c57998e765@4.4 Language: English Summary: Subjects: Science and Technology Keywords: Print Style: License: Creative commons Attribution License (by 4.0) Authors: OpenStax Microbiology Copyright Holders: OpenStax Microbiology Publishers: OpenStax Microbiology Latest Version: 4.4 First Publication Date: Oct 17, 2016 Latest Revision: Nov 11, 2016 Last Edited By:

OpenStax Microbiology

Date 11 November 2016

Source https://cnx.org/contents/5CvTdmJL@4.4

Author CNX OpenStax

 

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Description English: Enzyme changes shape by induced fit upon substrate binding to form enzyme-substrate complex. Hexokinase has a large induced fit motion that closes over the substrates adenosine triphosphate and xylose. Binding sites in blue, substrates in black and Mg2+ cofactor in yellow. (PDB: 2E2N​, 2E2Q)

Date 22 December 2015

Source Own work

Author Thomas Shafee

Other versions For raster version, see File:Hexokinase induced fit.png

Enzyme changes shape by induced fit upon substrate binding to form enzyme-substrate complex. Hexokinase has a large induced fit motion that closes over the substrates adenosine triphosphate and xylose. Binding sites in blue, substrates in black and Mg2+ cofactor in yellow.

Modified by A. G. DiGiovanna

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